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Epigenomics and Mechanisms Branch (EGM)

Publications

All recent publications: 2021-2015


  1. Cree, I. A., Indave Ruiz, B. I., Zavadil, J., McKay, J., Olivier, M., Kozlakidis, Z., . . . participants, I. R. (2021). The International Collaboration for Cancer Classification and Research. Int J Cancer. 148(3): 560-571. PMID: 32818326 doi: 10.1002/ijc.33260
  2. Liew, K., Yu, G. Q. S., Wei Pua, L. J., Wong, L. Z., Tham, S. Y., Hii, L. W., . . . Leong, C. O. (2021). Parallel genome-wide RNAi screens identify lymphocyte-specific protein tyrosine kinase (LCK) as a targetable vulnerability of cell proliferation and chemoresistance in nasopharyngeal carcinoma. Cancer Lett. 504: 81-90. PMID: 33587980 doi: 10.1016/j.canlet.2021.02.006
  3. Rao, A., Arvinden, V. R., Ramasamy, D., Patel, K., Meenakumari, B., Ramanathan, P., . . . Mani, S. (2021). Identification of novel dysregulated circular RNAs in early-stage breast cancer. J Cell Mol Med. 25(8): 3912-3921. PMID: 33544410 doi: 10.1111/jcmm.16324
  4. Alfano, R., Chadeau-Hyam, M., Ghantous, A., Keski-Rahkonen, P., Chatzi, L., Perez, A. E., . . . Plusquin, M. (2020). A multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism. Metabolism. 110: 154292. PMID: 32553738 doi: 10.1016/j.metabol.2020.154292
  5. Awada, Z., Nasr, R., Akika, R., Ghantous, A., Hou, L., & Zgheib, N. K. (2020). Effect of bisphenols on telomerase expression and activity in breast cancer cell lines. Mol Biol Rep. 47(5): 3541-3549. PMID: 32333245 doi: 10.1007/s11033-020-05444-0
  6. Chauvel, C., Novoloaca, A., Veyre, P., Reynier, F., & Becker, J. (2020). Evaluation of integrative clustering methods for the analysis of multi-omics data. Brief Bioinform. 21(2): 541-552. PMID: 31220206 doi: 10.1093/bib/bbz015
  7. Chung, F. F., & Herceg, Z. (2020). The Promises and Challenges of Toxico-Epigenomics: Environmental Chemicals and Their Impacts on the Epigenome. Environ Health Perspect. 128(1): 15001. PMID: 31950866 doi: 10.1289/EHP6104
  8. Claeys, L., Romano, C., De Ruyck, K., Wilson, H., Fervers, B., Korenjak, M., . . . Huybrechts, I. (2020). Mycotoxin exposure and human cancer risk: A systematic review of epidemiological studies. Compr Rev Food Sci Food Saf. 19(4): 1449-1464. PMID: 33337079 doi: 10.1111/1541-4337.12567
  9. De Ruyck, K., Huybrechts, I., Yang, S., Arcella, D., Claeys, L., Abbeddou, S., . . . De Saeger, S. (2020). Mycotoxin exposure assessments in a multi-center European validation study by 24-hour dietary recall and biological fluid sampling. Environ Int. 137: 105539. PMID: 32035364 doi: 10.1016/j.envint.2020.105539
  10. Eze, I. C., Jeong, A., Schaffner, E., Rezwan, F. I., Ghantous, A., Foraster, M., . . . Probst-Hensch, N. (2020). Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study. Environ Health Perspect. 128(6): 67003. PMID: 32484729 doi: 10.1289/EHP6174
  11. Foy, J. P., Bertolus, C., Boutolleau, D., Agut, H., Gessain, A., Herceg, Z., & Saintigny, P. (2020). Arguments to Support a Viral Origin of Oral Squamous Cell Carcinoma in Non-Smoker and Non-Drinker Patients. Front Oncol. 10: 822. PMID: 32528893 doi: 10.3389/fonc.2020.00822
  12. Gabriel, A. A. G., Mathian, E., Mangiante, L., Voegele, C., Cahais, V., Ghantous, A., . . . Foll, M. (2020). A molecular map of lung neuroendocrine neoplasms. Gigascience. 9(11). PMID: 33124659 doi: 10.1093/gigascience/giaa112
  13. Galati, L., Brancaccio, R. N., Robitaille, A., Cuenin, C., Luzi, F., Fiorucci, G., . . . Tommasino, M. (2020). Detection of human papillomaviruses in paired healthy skin and actinic keratosis by next generation sequencing. Papillomavirus Res. 9: 100196. PMID: 32222599 doi: 10.1016/j.pvr.2020.100196
  14. Galati, L., Combes, J. D., Gupta, P., Sen, R., Robitaille, A., Brancaccio, R. N., . . . Tommasino, M. (2020). Detection of a large spectrum of viral infections in conjunctival premalignant and malignant lesions. Int J Cancer. 147(10): 2862-2870. PMID: 32525572 doi: 10.1002/ijc.33149
  15. Gupta, P., Shahzad, N., Harold, A., Shuda, M., Venuti, A., Romero-Medina, M. C., . . . Tommasino, M. (2020). Merkel Cell Polyomavirus Downregulates N-myc Downstream-Regulated Gene 1, Leading to Cellular Proliferation and Migration. J Virol. 94(3): e00899-00819. PMID: 31694959 doi: 10.1128/jvi.00899-19
  16. Halaburkova, A., Cahais, V., Novoloaca, A., Araujo, M., Khoueiry, R., Ghantous, A., & Herceg, Z. (2020). Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes. Genome Res. 30(10): 1517-1532. PMID: 32963031 doi: 10.1101/gr.268292.120
  17. Hii, L. W., Chung, F. F., Mai, C. W., Yee, Z. Y., Chan, H. H., Raja, V. J., . . . Leong, C. O. (2020). Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1. Cells. 9(4): 23. PMID: 32260399 doi: 10.3390/cells9040886
  18. Hii, L. W., Chung, F. F., Soo, J. S., Tan, B. S., Mai, C. W., & Leong, C. O. (2020). Histone deacetylase (HDAC) inhibitors and doxorubicin combinations target both breast cancer stem cells and non-stem breast cancer cells simultaneously. Breast Cancer Res Treat. 179(3): 615-629. PMID: 31784862 doi: 10.1007/s10549-019-05504-5
  19. His, M., Biessy, C., Torres-Mejia, G., Angeles-Llerenas, A., Alvarado-Cabrero, I., Sanchez, G. I., . . . Rinaldi, S. (2020). Anthropometry, body shape in early-life and risk of premenopausal breast cancer among Latin American women: results from the PRECAMA study. Sci Rep. 10(1): 2294. PMID: 32042008 doi: 10.1038/s41598-020-59056-6
  20. Howe, C. G., Cox, B., Fore, R., Jungius, J., Kvist, T., Lent, S., . . . Breton, C. V. (2020). Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium. Diabetes Care. 43(1): 98-105. PMID: 31601636 doi: 10.2337/dc19-0524
  21. Koroknai, V., Szasz, I., Hernandez-Vargas, H., Fernandez-Jimenez, N., Cuenin, C., Herceg, Z., . . . Balazs, M. (2020). DNA hypermethylation is associated with invasive phenotype of malignant melanoma. Exp Dermatol. 29(1): 39-50. PMID: 31602702 doi: 10.1111/exd.14047
  22. Melki, P. N., Korenjak, M., & Zavadil, J. (2020). Experimental investigations of carcinogen-induced mutation spectra: Innovation, challenges and future directions. Mutat Res. 853: 503195. PMID: 32522347 doi: 10.1016/j.mrgentox.2020.503195
  23. Merid, S. K., Novoloaca, A., Sharp, G. C., Kupers, L. K., Kho, A. T., Roy, R., . . . Melen, E. (2020). Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med. 12(1): 25. PMID: 32114984 doi: 10.1186/s13073-020-0716-9
  24. Nalairndran, G., Hassan Abdul Razack, A., Mai, C. W., Fei-Lei Chung, F., Chan, K. K., Hii, L. W., . . . Leong, C. O. (2020). Phosphoinositide-dependent Kinase-1 (PDPK1) regulates serum/glucocorticoid-regulated Kinase 3 (SGK3) for prostate cancer cell survival. J Cell Mol Med. 24(20): 12188-12198. PMID: 32926495 doi: 10.1111/jcmm.15876
  25. Pashayan, N., Antoniou, A. C., Ivanus, U., Esserman, L. J., Easton, D. F., French, D., . . . Widschwendter, M. (2020). Personalized early detection and prevention of breast cancer: ENVISION consensus statement. Nat Rev Clin Oncol. 17(11): 687-705. PMID: 32555420 doi: 10.1038/s41571-020-0388-9
  26. Rodriguez-Aguilera, J. R., Ecsedi, S., Goldsmith, C., Cros, M. P., Dominguez-Lopez, M., Guerrero-Celis, N., . . . Hernandez-Vargas, H. (2020). Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor. Sci Rep. 10(1): 7822. PMID: 32385352 doi: 10.1038/s41598-020-64700-2
  27. Samet, J. M., Chiu, W. A., Cogliano, V., Jinot, J., Kriebel, D., Lunn, R. M., . . . Wild, C. P. (2020). The IARC Monographs: Updated Procedures for Modern and Transparent Evidence Synthesis in Cancer Hazard Identification. J Natl Cancer Inst. 112(1): 30-37. PMID: 31498409 doi: 10.1093/jnci/djz169
  28. Wang, C., Plusquin, M., Ghantous, A., Herceg, Z., Alfano, R., Cox, B., & Nawrot, T. S. (2020). DNA methylation of insulin-like growth factor 2 and H19 cluster in cord blood and prenatal air pollution exposure to fine particulate matter. Environ Health. 19(1): 129. PMID: 33287817 doi: 10.1186/s12940-020-00677-9
  29. Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., . . . Fernandez-Cuesta, L. (2019). Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids. Nat Commun. 10(1): 3407. PMID: 31431620 doi: 10.1038/s41467-019-11276-9
  30. Alfano, R., Guida, F., Galobardes, B., Chadeau-Hyam, M., Delpierre, C., Ghantous, A., . . . Plusquin, M. (2019). Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth cohort. Int J Epidemiol. 48(1): 30-44. PMID: 30590607 doi: 10.1093/ije/dyy259
  31. Awada, Z., Nasr, R., Akika, R., Cahais, V., Cuenin, C., Zhivagui, M., . . . Zgheib, N. K. (2019). DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer. Clin Epigenetics. 11(1): 138. PMID: 31601247 doi: 10.1186/s13148-019-0725-y
  32. Bodelon, C., Ambatipudi, S., Dugue, P. A., Johansson, A., Sampson, J. N., Hicks, B., . . . Garcia-Closas, M. (2019). Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies. Breast Cancer Res. 21(1): 62. PMID: 31101124 doi: 10.1186/s13058-019-1145-9
  33. Fernandez-Jimenez, N., Garcia-Etxebarria, K., Plaza-Izurieta, L., Romero-Garmendia, I., Jauregi-Miguel, A., Legarda, M., . . . Bilbao, J. R. (2019). The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. Sci Rep. 9(1): 1298. PMID: 30718669 doi: 10.1038/s41598-018-37746-6
  34. Fortuno, C., Cipponi, A., Ballinger, M. L., Tavtigian, S. V., Olivier, M., Ruparel, V., . . . James, P. A. (2019). A quantitative model to predict pathogenicity of missense variants in the TP53 gene. Hum Mutat. 40(6): 788-800. PMID: 30840781 doi: 10.1002/humu.23739
  35. Gruzieva, O., Xu, C. J., Yousefi, P., Relton, C., Merid, S. K., Breton, C. V., . . . Melen, E. (2019). Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. Environ Health Perspect. 127(5): 57012. PMID: 31148503 doi: 10.1289/ehp4522
  36. Herceg, Z., & Ambatipudi, S. (2019). Smoking-associated DNA methylation changes: no smoke without fire. Epigenomics. 11(10): 1117-1119. PMID: 31339344 doi: 10.2217/epi-2019-0136
  37. Holzl-Armstrong, L., Kucab, J. E., Korenjak, M., Luijten, M., Phillips, D. H., Zavadil, J., & Arlt, V. M. (2019). Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts. Methods Protoc. 2(4). PMID: 31766274 doi: 10.3390/mps2040085
  38. Jeong, A., Imboden, M., Ghantous, A., Novoloaca, A., Carsin, A. E., Kogevinas, M., . . . Probst-Hensch, N. (2019). DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma. Int J Environ Res Public Health. 16(4). PMID: 30791383 doi: 10.3390/ijerph16040600
  39. Johansson, A., Palli, D., Masala, G., Grioni, S., Agnoli, C., Tumino, R., . . . Flanagan, J. M. (2019). Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk. Clin Epigenetics. 11(1): 66. PMID: 31039828 doi: 10.1186/s13148-019-0664-7
  40. Josipovic, G., Tadic, V., Klasic, M., Zanki, V., Beceheli, I., Chung, F., . . . Zoldos, V. (2019). Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system. Nucleic Acids Res. 47(18): 9637-9657. PMID: 31410472 doi: 10.1093/nar/gkz709
  41. Korenjak, M., & Zavadil, J. (2019). Experimental identification of cancer driver alterations in the era of pan-cancer genomics. Cancer Sci. 110(12): 3622-3629. PMID: 31594033 doi: 10.1111/cas.14210
  42. Kupers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., . . . Felix, J. F. (2019). Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nat Commun. 10(1): 1893. PMID: 31015461 doi: 10.1038/s41467-019-09671-3
  43. Looi, C. K., Chung, F. F., Leong, C. O., Wong, S. F., Rosli, R., & Mai, C. W. (2019). Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment. J Exp Clin Cancer Res. 38(1): 162. PMID: 30987642 doi: 10.1186/s13046-019-1153-8
  44. Marques, M., Berrington, d. G. A., Beland, F., Browne, P., Demers, P., Lachenmeier, D., . . . Guyton, K. (2019). Advisory Group recommendations on priorities for the IARC Monographs. Lancet Oncol. 20(6): 763-764. PMID: 31005580 doi: 10.1016/s1470-2045(19)30246-3
  45. Mendy, M., Caboux, E., & Wild, C. P. (2019). Centralization of the IARC Biobank: Combining Multiple Sample Collections into a Common Platform. Biopreserv Biobank. 17(5): 433-443. PMID: 31091138 doi: 10.1089/bio.2018.0036
  46. Olivier, M., Bouaoun, L., Villar, S., Robitaille, A., Cahais, V., Heguy, A., . . . Rinaldi, S. (2019). Molecular features of premenopausal breast cancers in Latin American women: Pilot results from the PRECAMA study. PLoS ONE. 14(1): e0210372. PMID: 30653559 doi: 10.1371/journal.pone.0210372
  47. Paltiel, O., Lemeshow, S., Phillips, G. S., Tikellis, G., Linet, M. S., Ponsonby, A. L., . . . Dwyer, T. (2019). The association between birth order and childhood leukemia may be modified by paternal age and birth weight. Pooled results from the International Childhood Cancer Cohort Consortium (I4C). Int J Cancer. 144(1): 26-33. PMID: 30098208 doi: 10.1002/ijc.31635
  48. Patil, V., Cuenin, C., Chung, F., Aguilera, J. R. R., Fernandez-Jimenez, N., Romero-Garmendia, I., . . . Herceg, Z. (2019). Human mitochondrial DNA is extensively methylated in a non-CpG context. Nucleic Acids Res. 47(19): 10072-10085. PMID: 31665742 doi: 10.1093/nar/gkz762
  49. Perrier, F., Viallon, V., Ambatipudi, S., Ghantous, A., Cuenin, C., Hernandez-Vargas, H., . . . Romieu, I. (2019). Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study. Clin Epigenetics. 11(1): 57. PMID: 30940212 doi: 10.1186/s13148-019-0637-x
  50. Pez, F., Gifu, P., Degli-Esposti, D., Fares, N., Lopez, A., Lefrancois, L., . . . Caron de Fromentel, C. (2019). In vitro transformation of primary human hepatocytes: Epigenetic changes and stemness properties. Exp Cell Res. 384(2): 111643. PMID: 31557464 doi: 10.1016/j.yexcr.2019.111643
  51. Reimann, B., Janssen, B. G., Alfano, R., Ghantous, A., Espin-Perez, A., de Kok, T. M., . . . Plusquin, M. (2019). The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome. Front Genet. 10: 325. PMID: 31031804 doi: 10.3389/fgene.2019.00325
  52. Sikdar, S., Joehanes, R., Joubert, B. R., Xu, C. J., Vives-Usano, M., Rezwan, F. I., . . . London, S. J. (2019). Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics. 11(13): 1487-1500. PMID: 31536415 doi: 10.2217/epi-2019-0066
  53. Silva, I. R., Ramos, M., Arantes, L., Lengert, A. V. H., Oliveira, M. A., Cury, F. P., . . . Silveira, H. C. S. (2019). Evaluation of DNA Methylation Changes and Micronuclei in Workers Exposed to a Construction Environment. Int J Environ Res Public Health. 16(6). PMID: 30871143 doi: 10.3390/ijerph16060902
  54. Vargas-Ayala, R. C., Jay, A., Manara, F., Maroui, M. A., Hernandez-Vargas, H., Diederichs, A., . . . Accardi, R. (2019). Interplay between the Epigenetic Enzyme Lysine (K)-Specific Demethylase 2B and Epstein-Barr Virus Infection. J Virol. 93(13). PMID: 30996097 doi: 10.1128/JVI.00273-19
  55. Zavadil, J., & Rozen, S. G. (2019). Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention. Chem Res Toxicol. 32(11): 2153-2155. PMID: 31509385 doi: 10.1021/acs.chemrestox.9b00339
  56. Zhivagui, M., Ng, A. W. T., Ardin, M., Churchwell, M. I., Pandey, M., Renard, C., . . . Zavadil, J. (2019). Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans. Genome Res. 29(4): 521-531. PMID: 30846532 doi: 10.1101/gr.242453.118
  57. Alfano, R., Herceg, Z., Nawrot, T. S., Chadeau-Hyam, M., Ghantous, A., & Plusquin, M. (2018). The Impact of Air Pollution on Our Epigenome: How Far Is the Evidence? (A Systematic Review). Curr Environ Health Rep. 5(4): 544-578. PMID: 30361985 doi: 10.1007/s40572-018-0218-8
  58. Aushev, V. N., Lee, E., Zhu, J., Gopalakrishnan, K., Li, Q., Teitelbaum, S. L., . . . Chen, J. (2018). Novel Predictors of Breast Cancer Survival Derived from miRNA Activity Analysis. Clin Cancer Res. 24(3): 581-591. PMID: 29138345 doi: 10.1158/1078-0432.Ccr-17-0996
  59. Barouki, R., Melen, E., Herceg, Z., Beckers, J., Chen, J., Karagas, M., . . . Nohara, K. (2018). Epigenetics as a mechanism linking developmental exposures to long-term toxicity. Environ Int. 114: 77-86. PMID: 29499450 doi: 10.1016/j.envint.2018.02.014
  60. Brancaccio, R. N., Robitaille, A., Dutta, S., Cuenin, C., Santare, D., Skenders, G., . . . Gheit, T. (2018). Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types. Virology. 520: 1-10. PMID: 29747121 doi: 10.1016/j.virol.2018.04.017
  61. Demetriou, C. A., Degli Esposti, D., Fedinick, K. P., Russo, F., Robinson, O., & Vineis, P. (2018). Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective. Eur J Clin Invest. 48(6): 12. PMID: 29604052 doi: 10.1111/eci.12933
  62. Felix, J. F., Joubert, B. R., Baccarelli, A. A., Sharp, G. C., Almqvist, C., Annesi-Maesano, I., . . . London, S. J. (2018). Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol. 47(1): 22-23u. PMID: 29025028 doi: 10.1093/ije/dyx190
  63. Fiorito, G., Vlaanderen, J., Polidoro, S., Gulliver, J., Galassi, C., Ranzi, A., . . . Naccarati, A. (2018). Oxidative stress and inflammation mediate the effect of air pollution on cardio- and cerebrovascular disease: A prospective study in nonsmokers. Environ Mol Mutagen. 59(3): 234-246. PMID: 29114965 doi: 10.1002/em.22153
  64. Fortuno, C., James, P. A., Young, E. L., Feng, B., Olivier, M., Pesaran, T., . . . Spurdle, A. B. (2018). Improved, ACMG-compliant, in silico prediction of pathogenicity for missense substitutions encoded by TP53 variants. Hum Mutat. 39(8): 1061-1069. PMID: 29775997 doi: 10.1002/humu.23553
  65. George, J., Walter, V., Peifer, M., Alexandrov, L. B., Seidel, D., Leenders, F., . . . Thomas, R. K. (2018). Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors. Nat Commun. 9(1): 1048. PMID: 29535388 doi: 10.1038/s41467-018-03099-x
  66. Ghantous, A., Hernandez-Vargas, H., & Herceg, Z. (2018). DNA Methylation Analysis from Blood Spots: Increasing Yield and Quality for Genome-Wide and Locus-Specific Methylation Analysis. Methods Mol Biol. 1708: 605-619. PMID: 29224166 doi: 10.1007/978-1-4939-7481-8_31
  67. Herceg, Z., Ghantous, A., Wild, C. P., Sklias, A., Casati, L., Duthie, S. J., . . . Hernandez-Vargas, H. (2018). Roadmap for investigating epigenome deregulation and environmental origins of cancer. Int J Cancer. 142(5): 874-882. PMID: 28836271 doi: 10.1002/ijc.31014
  68. Jeong, A., Fiorito, G., Keski-Rahkonen, P., Imboden, M., Kiss, A., Robinot, N., . . . Probst-Hensch, N. (2018). Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases. Environ Int. 119: 334-345. PMID: 29990954 doi: 10.1016/j.envint.2018.06.025
  69. Mostafavi, N., Vermeulen, R., Ghantous, A., Hoek, G., Probst-Hensch, N., Herceg, Z., . . . Vlaanderen, J. (2018). Acute changes in DNA methylation in relation to 24h personal air pollution exposure measurements: A panel study in four European countries. Environ Int. 120: 11-21. PMID: 30055357 doi: 10.1016/j.envint.2018.07.026
  70. Perrier, F., Novoloaca, A., Ambatipudi, S., Baglietto, L., Ghantous, A., Perduca, V., . . . Ferrari, P. (2018). Identifying and correcting epigenetics measurements for systematic sources of variation. Clin Epigenetics. 10: 38. PMID: 29588806 doi: 10.1186/s13148-018-0471-6
  71. Plusquin, M., Chadeau-Hyam, M., Ghantous, A., Alfano, R., Bustamante, M., Chatzi, L., . . . Vineis, P. (2018). DNA Methylome Marks of Exposure to Particulate Matter at Three Time Points in Early Life. Environ Sci Technol. 52(9): 5427-5437. PMID: 29597345 doi: 10.1021/acs.est.7b06447
  72. Romero-Garmendia, I., Garcia-Etxebarria, K., Hernandez-Vargas, H., Santin, I., Jauregi-Miguel, A., Plaza-Izurieta, L., . . . Bilbao, J. R. (2018). Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease. Genes (Basel). 9(5). PMID: 29748492 doi: 10.3390/genes9050245
  73. Romieu, I., Biessy, C., Carayol, M., His, M., Torres-Mejia, G., Angeles-Llerenas, A., . . . Rinaldi, S. (2018). Reproductive factors and molecular subtypes of breast cancer among premenopausal women in Latin America: the PRECAMA study. Sci Rep. 8(1): 13109. PMID: 30166604 doi: 10.1038/s41598-018-31393-7
  74. Talukdar, F. R., di Pietro, M., Secrier, M., Moehler, M., Goepfert, K., Lima, S. S. C., . . . Herceg, Z. (2018). Molecular landscape of esophageal cancer: implications for early detection and personalized therapy. Ann N Y Acad Sci. 1434(1): 342-359. PMID: 29917250 doi: 10.1111/nyas.13876
  75. Tikellis, G., Dwyer, T., Paltiel, O., Phillips, G. S., Lemeshow, S., Golding, J., . . . Linet, M. S. (2018). The International Childhood Cancer Cohort Consortium (I4C): A research platform of prospective cohorts for studying the aetiology of childhood cancers. Paediatr Perinat Epidemiol. 32(6): 568-583. PMID: 30466188 doi: 10.1111/ppe.12519
  76. Uribe, D., Cardona, A., Esposti, D. D., Cros, M. P., Cuenin, C., Herceg, Z., . . . Cortes-Mancera, F. M. (2018). Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines. Ann Hepatol. 17(3): 444-460. PMID: 29735783 doi: 10.5604/01.3001.0011.7389
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