Infections and Cancer Epidemiology Group
The overall strategic vision for the Infections and Cancer Epidemiology Group (ICE) is to improve the epidemiological evidence base with respect to prevention of infection-attributable cancers. This is achieved through global collaborations that bring together partners from both low- and middle-income countries and high-income countries.
The research strategy of ICE relies on obtaining both high-quality data and biological samples from epidemiologically well-characterized populations. Given the disproportionate burden of infection-attributable cancers in low- and middle-income countries (up to 25% of all cancer cases in large parts of Asia and Africa), although ICE’s strategy is global, the work naturally focuses on these regions of the world.
Currently, 11 infectious agents are classified as carcinogenic (Group 1) by the IARC Monographs programme, each at a different stage along the pathway from discovery to public health intervention, and a few infectious agents that are suspected to be carcinogenic are priorities for future IARC Monographs evaluations. Correspondingly, ICE’s research includes a wide portfolio of study designs, tailored to specific infectious agents, across a spectrum of epidemiological research from etiology and natural history, through global burden assessment, to evaluation and modelling of the impact of interventions and policy.